Using Small-angle X-ray scattering (SAXS) to efficiently and quickly image large protein molecular assemblies, scientists have designed a hollow, cube-shaped protein cage that has the potential for delivering proteins or other chemicals to specific locations for medical, energy, and other applications. The nanocage crystal structure was optimized at the Advanced Light Source (Image courtesy of Greg Hura, LBNL).
Lai, Y.T., E. Reading, G.L. Hura, K.L.Tsai, A. Laganowsky, F.J. Asturias, J.A. Tainer, C.V. Robinson, and T.O. Yeates. 2014.“Structure of a Designed Protein Cage that Self-Assembles into a Highly Porous Cube,” Nature Chemistry 6, 1065–1071. doi:10.1038/nchem.2107