Structural biology and imaging resources are key capabilities within the Department of Energy’s (DOE) Biological and Environmental Research (BER) program’s systems biology toolbox for predictively understanding the relationships among the genome, structure, function, and environmental interactions of plants and microbes important for energy and environmental missions. These integrated suites of experimental and computational capabilities examine biological molecules at resolutions and scales uniquely provided at DOE synchrotron and neutron user facilities.
BER supports a portfolio of research technologies, methodologies, and instruments at these DOE synchrotron and neutron user facilities. These resources enable experiments for studying and understanding structural and functional processes of importance to BER–funded investigators and centers.
The spatial and temporal resolutions available from neutron and photon beams enable unprecedented characterization and imaging of interactions among plants, microbes, and the environment. Accessible scales range from subnanometer to millimeter length and over time dimensions from femtoseconds to seconds. Capabilities to provide molecular fingerprints and mechanistic and dynamic understanding of in situ processes help advance various high–priority BER science focus areas.
The BER-funded facility resources described on this site seek to promote and expand collaborations between them and the BER research community. These interactions will enable and facilitate the necessary fundamental science to understand, predict, manipulate, and design biological processes that underpin innovations in DOE’s biological energy and environmental missions. This website serves as a portal for information on these resources and their capabilities, how to access them, and highlights of scientific accomplishments achieved as a result of these BER-supported resources.